PREMAS Biotech - CRO in India - Contract research services and biomanufacturing services
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Premas Biotech has launched new and innovative products for the biology and drug discovery markets:

a) Vectors

Premas Biotech has launched a host of new vectors for:
  • Bacterial systems
  • Yeast systems
  • Mammalian systems

The hallmark of these vectors are that they have excellent expression profile, especially in the expression of membrane proteins or membrane associated proteins. (more...)

b) Drug Metabolism Enzymes

Premas Biotech has launched the drug metabolism enzymes also known as CYP P450 suite of enzymes. Premas Biotech has co-expressed the major human drug metabolizing enzymes (DME’s) along with human NADPH-dependent cytochrome P450 reductase in Saccharomyces cerevisiae (yeast host system). The yeast system enables efficient expression of complex, multi-subunit proteins along with post- translational processing which essentially mimics the human system. Recombinant expression is advantageous on the basis that the presence of a single enzyme enables for specific applications and read-outs required in drug metabolism and drug-drug interactions. (more...)

c) Reporter Gene Assays (RGAs)

Premas Biotech has launched two different RGAs:
  • RGA for Angiogenic Potential of a compound/NCE: this assay evaluates the Angiogenic potential of a compound or new chemical entity, and gives a fluorescent or lumniscence readout depending on the reporter gene. (more...)
  • RGA for determination of heavy metal content of a mixture/formulation: this assay evaluates the presence and toxicity of heavy metals in a formulation/mixture and gives a fluorescent or lumniscence readout depending on the reporter gene. (more...)
  • Customised Assay Development: At Premas Biotech, we are developing a number of RGA and biochemical assays for our customers. (more...)

d) Nucleic Acid Purification kits

Premas Biotech has developed two unique kits:
  • Plant genomic DNA isolation kit: The kit does not require the use of column and is completely free of hazardous buffer chemicals/chemistry, like CTAB, etc, and does not use phenol/chloroform steps either. Furthermore, the kit can isolate genomic DNA from any part of the plant, roots, seeds, stems, flowers, leaves, stigma, stamens, etc. . (more...)
  • Mycobacterium Genomic DNA isolation kit: This innovative kit has been developed to isolate Mycobacterium tuberculosis genomic DNA. It is well documented that mycobacterium genomic DNA isolation is difficult due to presence of interfering factors like tough cell wall, etc.

Premas Biotech has managed to resolve the issues and have launched the MTB kit which does not require the use of column. This kit has been demonstrated to be effective for genomic DNA isolation from all sample sources, sputum, blood, tissues, etc. (more...)

vectors
DME’s
RGAs Assays
DNA isolation Kits